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The Popkin Method

About the show.

You’re not crazy. Your care is just fragmented. Most people bounce between specialists, apps, and online “biohacks” without ever getting real answers. The Popkin Method is here to change that - with real, physician-led medicine that integrates the best of internal and functional approaches into one clear, personalized care. Hosted by Matthew C. Popkin, M.D., a board-certified internist with surgical training and functional medicine expertise - this podcast explores how to reconnect the dots between your symptoms, labs, lifestyle, and deeper health goals. Whether you're battling fatigue, inflammation, hormones, weight, or aging - this show delivers clinical insight, clarity, and next steps… with none of the hype. Real medicine. Real results. Real transformation.

About the host.

Dr. Matthew C. Popkin — Internal Medicine Physician. Matthew C. Popkin, M.D. is not your typical physician - and that’s exactly the point. A highly skilled physician with world-class training, Matthew C. Popkin, M.D. attended medical school at the University of Miami School of Medicine, completed his general and orthopedic surgery training at Mount Sinai Medical Center… Read the full profile →

Featured episodes.

3 hand-picked videos
Featured video 1
(coming soon)
Featured video 2
(coming soon)
Featured video 3
(coming soon)

Latest episodes.

newest first
Ep 19 · Aug 10, 2026 · 39 min

Combining Internal and Functional Medicine for Lasting Wellness with the Popkin Method

Welcome to another episode of The Popkin Method, where Dr. Matthew C. Popkin dives deep into the science and practical application of living your healthiest life. In today’s episode, we move beyond medical jargon and buzzwords to show how foundational…

Ep 18 · Jul 23, 2026 · 35 min

How to Restore Your Physiology: The Popkin Method Approach to Lasting Health

Welcome back to The Popkin Method, the show where science meets hope and practical strategies drive lifelong transformation. In today’s episode, Dr. Matthew C. Popkin pulls back the curtain on how real patients experience medicine beyond theory, unpacking…

Ep 17 · Jul 10, 2026 · 1 hr 5 min

Your Biggest Health Questions Answered: Supplements, Skin, Blood Pressure, Brain Health, and Peptides

Welcome back to The Popkin Method Podcast, where we break down the science of health, longevity, performance, weight loss, and healthy aging into simple, actionable principles. In this special Q&A episode, Dr. Matthew Popkin answers your most pressing…

Ep 16 · Jun 19, 2026 · 56 min

Navigating Menopause: The Popkin Method Approach to Hormones, Metabolism, and Women’s Longevity

Welcome back to The Popkin Method, where we connect symptoms to science, and science to solutions. In today’s episode, we're tackling one of the biggest blind spots in modern medicine: perimenopause and menopause. Millions of women are told their labs are…

Ep 15 · May 29, 2026 · 56 min

Beyond Peptides: Building a Lasting Weight Loss Foundation with the Popkin Method

Welcome to The Popkin Method, where we cut through the noise of miracle weight loss solutions and trendy shortcuts dominating social media and advertising today. In this episode, Dr. Matthew C. Popkin takes a deep, clinical dive into GLP-1-based therapies…

Ep 14 · May 20, 2026 · 1 hr 14 min

Demystifying Fatty Liver Disease: The Four-Phase Popkin Method for Sustainable Metabolic Health

Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles one of the most misunderstood, yet critical, obstacles to lasting weight loss and wellness: fatty liver disease. Most people think of it as just a byproduct of poor diet or…

Ep 13 · Apr 30, 2026 · 54 min

Unlocking the Cellular Secrets of Aging: How NAD Fuels Longevity from the Inside Out

Welcome back to The Popkin Method! In this episode, Dr. Matthew C. Popkin takes us beyond the surface of anti-aging, exploring the science of aging from the inside out. We’re all familiar with visible signs like wrinkles and graying hair, but what really…

Ep 12 · Apr 18, 2026 · 38 min

Building Sustainable Care Plans: The Popkin Method Approach to Lasting Health

Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles one of the biggest challenges in modern healthcare: making care plans that truly stick. Most people don’t fail their health plans; the plans fail them, often because they’re…

Ep 11 · Mar 27, 2026 · 53 min

Demystifying Hormone Optimization Therapy for Men and Women with the Popkin Method

Welcome to another episode of The Popkin Method, where we’re passionate about restoring physiology, preserving lean muscle mass, stabilizing your metabolism, and building long-term resilience from the inside out. This week, Dr. Popkin tackles one of the most…

Ep 10 · Mar 13, 2026 · 50 min

Reversing Chronic Inflammation: The Popkin Method’s Three-Phase Approach for Better Health

Welcome back to The Popkin Method! In this episode, host Dr. Matthew C. Popkin dives deep into one of the most important yet misunderstood topics in modern health: whole body systemic inflammation. You’ll discover what chronic inflammation really is, how it…

Ep 9 · Feb 26, 2026 · 1 hr 1 min

Blood Sugar Chaos: How Stabilizing Glucose Unlocks Lasting Energy, Gut Health, and Calm

Welcome back to The Popkin Method! In this episode, Dr. Matthew C. Popkin explores the real reasons behind energy crashes, anxiety, cravings, and stubborn gut issues, the hidden chaos of blood sugar instability. Most of us only think about blood sugar in the…

Ep 8 · Feb 10, 2026 · 37 min

Healing an Overwhelmed Gut: Stress, Food, and the Popkin Method Approach

Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles a myth that so many people struggle with: the belief that their gut is broken for good. But is it really? Or is your gut just overwhelmed and crying out for support? You’ll…

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